About FUNCTIon

About FUNCTIon

The FUNCTIon trial is a multi-institutional, randomized controlled trial comparing the functional outcome of pouch surgery in patients with ulcerative colitis (UC) or inflammatory Bowel Disease unclassified (IBDu). This study is sponsored by a research grant from the International Organization for the study of Inflammatory Bowel Diseases (IOIBD) and recruits patients at Mount Sinai hospital Toronto, Cedars Sinai Hospital (Los Angeles, USA), University Leuven (Belgium) and St-Marks Hospital (London, UK).

Trial registration at clinicaltrials.gov
Registration number: NCT04722757 

Objective

The objective of this study is to determine if pouch-related functional outcomes following transanal ileal pouch anal anastomosis (ta-IPAA) are not worse than a transabdominal approach (tabd-IPAA) at one year after surgery in UC and IBDu.

Secondary objective is to assess pouch-related functional outcome measured at several intervals within a year from surgery.